Targeting Human Mitochondrial NAD(P)+-Dependent-Malic Enzyme (ME2) , Sirtuin 1 (SIRT1) and Cyclooxygenase-2 (COX-2) in Lung and Breast Cancer Cells : A Novel Chemotherapeutic Approach Depending on p53 Expression Status
碩士 === 國立中興大學 === 生命科學系所 === 103 === There are three isoforms in malic enzymes (MEs) family which include ME1, ME2 and ME3. Mitochondrial NAD(P)+-dependent malic enzyme (ME2) is particularly expressed in tumor mitochondria and rather than normal cells . ME2 catalyzes substrate malate to generate pyr...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2015
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| Online Access: | http://ndltd.ncl.edu.tw/handle/15313558750116910911 |