Progranulin promotes Temozolomide resistance of Glioblastoma by orchestrating DNA repair and tumor stemness

博士 === 國立陽明大學 === 生化暨分子生物研究所 === 102 === Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adult with a dismal prognosis. Current therapy of surgical removal combined with Temozolomide (TMZ) and radiation therapy only slightly prolongs the survival of GBM patients. In this st...

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Bibliographic Details
Main Authors: Irfan Naseem Bandey, 潘爾納
Other Authors: Pang-Hsien Tu
Format: Others
Language:en_US
Published: 2014
Online Access:http://ndltd.ncl.edu.tw/handle/82581358178246767096