I.Aliphatic Hydroxamates Capped with Substituted Aryl Indole as Histone Deacetylase InhibitorsII.Structure Optimization for Ortho-Aryl N-Hydroxycinnamides as HDAC 8 Isoform-Selective Inhibitors against Cancer CellsII.Structure Optimization forOrtho-Aryl N-Hydroxycinnamides as
碩士 === 臺北醫學大學 === 生藥學研究所 === 102 === Histone deacetylase (HDAC) inhibitors are regarded as a promising therapeutic for treatment of cancer. However, current HDAC inhibitors have some unsatisfactory problems, including limited potency for solid tumors and dose-limiting side effects. This study includ...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2014
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| Online Access: | http://ndltd.ncl.edu.tw/handle/55xw6v |