Synthesis of Water-soluble IMD-0354 Derivatives and Evaluating Their IKKβ Inhibition
碩士 === 東海大學 === 化學系 === 102 === NF-κB is a transcription factor that controls the expression of genome involved in immune responses, apoptosis and cell cycle. In cytoplasm, NF-κB is inhibitid by IκB, but would be activated upon phosphorylation by IKKβ. In previous study, IMD-0354 and its derivatives...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2013
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| Online Access: | http://ndltd.ncl.edu.tw/handle/43227561410254100674 |