Effect of Sialylation on EGFR Function and Resistance to Tyrosine Kinase Inhibitor Gefitinib
博士 === 國立臺灣大學 === 生化科學研究所 === 102 === Epidermal growth factor receptor (EGFR) is a heavily glycosylated transmembrane receptor tyrosine kinase. Upon EGF-binding, EGFR commences conformational changes to dimerize, which results in kinase activation and auto-phosphorylation, and the activation of down...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2014
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| Online Access: | http://ndltd.ncl.edu.tw/handle/96388378231788773608 |