Investigating the Effect of TSCA-001 on Spinocerebellar Ataxia 3 Disease Using Zebrafish and Transgenic Mice Model

碩士 === 國立東華大學 === 生命科學系 === 102 === Abstract Spinocerebellar ataxia type 3 (SCA3) is a neurodegenerative disease caused by an expansion of CAG sequence repeats on the ATXN3 gene and further leading to the aggregation of abnormal ataxin-3 (ATXN3) protein. The disease can be characterized by the degen...

Full description

Bibliographic Details
Main Authors: Cheng-Han Wu, 吳政翰
Other Authors: Tzyy-Wen Chiou
Format: Others
Published: 2014
Online Access:http://ndltd.ncl.edu.tw/handle/r9chxc