The mechanism of KIT exon 11 557-558 deletion for liver metastasis in gastrointestinal stromal tumors
碩士 === 國立成功大學 === 臨床醫學研究所 === 102 === Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the digestive tract. KIT, a receptor tyrosine kinase, is expressed in the most of GISTs (95%). Binding of the stem cell factor (SCF), the ligand of KIT, activate downstream signali...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2014
|
Online Access: | http://ndltd.ncl.edu.tw/handle/b5fh2v |