The mechanism of KIT exon 11 557-558 deletion for liver metastasis in gastrointestinal stromal tumors

碩士 === 國立成功大學 === 臨床醫學研究所 === 102 === Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the digestive tract. KIT, a receptor tyrosine kinase, is expressed in the most of GISTs (95%). Binding of the stem cell factor (SCF), the ligand of KIT, activate downstream signali...

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Bibliographic Details
Main Authors: Tzu-YingLi, 李姿瑩
Other Authors: Kai-Hsi Hsu
Format: Others
Language:en_US
Published: 2014
Online Access:http://ndltd.ncl.edu.tw/handle/b5fh2v