Evaluating the Antitumor Activity of Indolizino[6,7-b]indoles against Chemoresistant Cancer Cells

碩士 === 國立陽明大學 === 生物藥學研究所 === 101 === A series of indolizino[6,7-b]indole derivatives were designed and synthesized as hybrid molecules of β-carboline, a moiety with topoisomerase inhibitory activity, and bis(hydroxymethyl)pyrrole, a DNA cross-linking moiety. The antitumor activities of these compou...

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Bibliographic Details
Main Authors: Yi-Fan Chen, 陳羿帆
Other Authors: Te-Chang Lee
Format: Others
Language:en_US
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/85240390286697634824