Mechanism of suppressing HCT116 colorectal cancer cell growth by hMMS21-depletion

碩士 === 國立陽明大學 === 生化暨分子生物研究所 === 101 === hMMS21 also called Nse2 (non-SMC element 2) is a SUMO E3 ligase. According to the research, MMS21 plays a role in DNA damage repair. Our previous study demonstrated that hMMS21 depletion in MCF7 breast cancer cells reduced E2F1 protein level, and cyclin E-CDK...

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Bibliographic Details
Main Authors: Wei-Hsiang Cheng, 鄭偉祥
Other Authors: Jim C. Fong
Format: Others
Language:zh-TW
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/16265403591947728104