The involvement of RhoA signaling and microtubule stability in oncogenic Shp2-induced epithelial defects
博士 === 國立臺灣大學 === 生物化學暨分子生物學研究所 === 101 === Deregulation of Shp2, a non-receptor tyrosine phosphatase, causes hyper-activation of extracellular signal-regulated kinase (ERK), leading to growth abnormality. I found that oncogenic Shp2 expression decreased microtubule (MT) stability to up-regulate ERK...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2013
|
| Online Access: | http://ndltd.ncl.edu.tw/handle/36999568467658488130 |