Evaluation of effect of HDAC inhibitors on SCA17 with SCA17 mouse slice culture and transgenic mice
碩士 === 國立臺灣師範大學 === 生命科學研究所 === 101 === Spinocerebellar ataxia type 17 (SCA17) is a polyQ neurodegenerative disease caused by abnormal CAG repeat expansion of TATA-box binding protein (TBP) gene. The CAG trinucleotide expansion results in the mutant polyQ TBP protein misfolded and accumulated in the...
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| Format: | Others |
| Language: | en_US |
| Published: |
2013
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| Online Access: | http://ndltd.ncl.edu.tw/handle/06941418884344658241 |