Modulate polyglutamine protein aggregation by Trigger factor and FKBP12

碩士 === 國立中央大學 === 化學學系 === 101 === Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by the mutational expansion of CAG triplet repeat in mutant Huntingtin (mHTT) protein. These proteins form aggregates in the affected neurons of patient brains that correlate wit...

Full description

Bibliographic Details
Main Authors: YI-NI LI, 李宜妮
Other Authors: Joseph Jen-Tse Huang
Format: Others
Language:zh-TW
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/68461287922832798868