Study the mechanisms underlying the cell death enhancement by loading small molecule inhibitors into PLGA nanoparticles

博士 === 國立成功大學 === 基礎醫學研究所 === 101 === LY294002 (LY) is a potent inhibitor of phosphatidylinositol 3-kinases (PI3Ks); however, bio-applications of LY are limited by its poor solubility and pharmacokinetic profile. Poly (lactic-co-glycolic acid) (PLGA) is a biodegradable nanomaterial that can be used...

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Bibliographic Details
Main Authors: Chia-ChengHou, 侯佳成
Other Authors: Wu-Chou Su
Format: Others
Language:en_US
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/55850178101244167471