Pathological role of HLA-B*1502 in carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis
博士 === 國立陽明大學 === 生化暨分子生物研究所 === 100 === Increasing studies revealed that HLA alleles are the major genetic determinants of drug hypersensitivity; however, the underlying molecular mechanism remains unclear. Here, we adopt the HLA-B*1502 genetic predisposition to carbamazepine (CBZ)-induced Stevens-...
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| Format: | Others |
| Language: | en_US |
| Published: |
2012
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| Online Access: | http://ndltd.ncl.edu.tw/handle/53019387631640777046 |