Elucidation of mechanism underlying TAR DNA-binding protein 43 (TDP-43) aggregation: implications for its pathogenic role in neurodegenerative diseases

博士 === 國立陽明大學 === 生化暨分子生物研究所 === 100 === TAR DNA-binding protein 43 (TDP-43) is a nuclear RNA/DNA-binding protein that is important for neuronal functions through regulating gene transcription, mRNA splicing, mRNA stability and microRNA biogenesis. Several neurodegenerative diseases including amyotr...

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Bibliographic Details
Main Authors: Huei-Ying Li, 李慧瑛
Other Authors: Pang-Hsien Tu
Format: Others
Language:en_US
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/48503430643105160070