Elucidation of mechanism underlying TAR DNA-binding protein 43 (TDP-43) aggregation: implications for its pathogenic role in neurodegenerative diseases
博士 === 國立陽明大學 === 生化暨分子生物研究所 === 100 === TAR DNA-binding protein 43 (TDP-43) is a nuclear RNA/DNA-binding protein that is important for neuronal functions through regulating gene transcription, mRNA splicing, mRNA stability and microRNA biogenesis. Several neurodegenerative diseases including amyotr...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2011
|
Online Access: | http://ndltd.ncl.edu.tw/handle/48503430643105160070 |