Important Role of the ß Strands of RRM2 Domain in the Pathological TDP-43 Aggregate Formation

碩士 === 國立陽明大學 === 生命科學系暨基因體科學研究所 === 100 === TAR-DNA-binding protein-43 (TDP-43) is a ubiquitously expressed nuclear protein highly conserved among C. elegans, Drosophila, mouse and human. Structurally, TDP-43 contains two RNA-recognition motifs (RRMs) and a glycine-rich domain (GRD). TDP-43 has bee...

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Bibliographic Details
Main Authors: Jhe-Ruei Liang, 梁哲睿
Other Authors: Che-Kun James Shen
Format: Others
Language:en_US
Published: 2012
Online Access:http://ndltd.ncl.edu.tw/handle/37898426293401717865