Studies on the synthesis of IMD-0354 derivatives and their inhibition to transcription factor NF-κB.

碩士 === 東海大學 === 化學系 === 100 === Nuclear factor-κB ( NF-κB ) is an important transcription factor. The cell is stimulated by stress, cytokines and toxic metals, leading to NF-κB activation and overexpress of NF-κB would result in prolification of cell or development of tumor. We took a novel potentia...

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Bibliographic Details
Main Authors: Hsieh, Onde, 謝正鴻
Other Authors: 吳雨珊
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/79584573414720262145