Unraveling the structural characteristics of wild-type and mutant D178N of soluble dimeric prion protein at different pH values and temperatures: A molecular dynamics study

碩士 === 國立成功大學 === 工程科學系碩博士班 === 100 === Prion disease is neurodegenerative diseases, also called transmissible spongiform encephalopathies (TSE). Such neurodegeneration event produces the structural misfolding from nomal PrPC to the pathogenic PrPSc. At present the PrPC how to transform into PrPSc p...

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Bibliographic Details
Main Authors: Yung-YangChang, 張永源
Other Authors: Chi-Chuan Hwang
Format: Others
Language:zh-TW
Published: 2012
Online Access:http://ndltd.ncl.edu.tw/handle/56951004451010529433