Mass spectrometric analysis of (1) glyoxal-induced DNA cross-links, (2) glyoxal-, methylglyoxal-, peroxynitrite-induced post-translational modifications of human hemoglobin, and (3) nitrated and nitrosylated human urinary proteins.

博士 === 國立中正大學 === 化學暨生物化學研究所 === 100 === Glyoxal and methylglyoxal are mutagens and they react with biological molecules. Glyoxal reacts with DNA to generate DNA crosslinked products, include dG-gx-dC, dG-gx-dG, and dG-gx-dA. In this study, we use capillary liquid chromatography nanospray ionization...

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Bibliographic Details
Main Authors: Chen, Yu-Chin, 陳育進
Other Authors: Chen, Hauh-Jyun Candy
Format: Others
Language:zh-TW
Published: 2012
Online Access:http://ndltd.ncl.edu.tw/handle/74837823965403461737