Quantitative Assay for Ethylpurine Adducts in Human White Blood Cells DNA and Human Urine by Stable Isotope Dilution Capillary LC-Nanospray Ionization Tandem Mass Spectrometry
碩士 === 國立中正大學 === 化學暨生物化學研究所 === 100 === Cigarette smoke contains many alkylating agents which damage DNA producing DNA adducts, such as 3-ethyladenine (3-EtA) and 7-ethylguanine (7-EtG). To quantify ethylated adducts on DNA, I used neutral thermal hydrolysis to release 3-EtA and 7-EtG from DNA. The...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2012
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| Online Access: | http://ndltd.ncl.edu.tw/handle/26809395868158430724 |