Identification of Rad as a p53 direct target and characterization of its functional significance

博士 === 國立陽明大學 === 生化暨分子生物研究所 === 99 === Tumor suppressor p53, a transcriptional activator, maintains genome integrity by mediating the expression of downstream targets. Here we show that the Rad , Ras-related associated with diabetes, is a bona fide target of p53. Overexpression of p53 upregulates t...

Full description

Bibliographic Details
Main Authors: Bo-Yuan Hsiao, 蕭博元
Other Authors: Fung-Fang Wang
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/75568708111176012279