Comparison of Amyloid Fibrils Formed by Wild-Type and P137A Mutant of 127–147 Fragment of Human Prion Protein

碩士 === 國立臺灣大學 === 化學研究所 === 99 === Prion protein (PrP) is an infectious species that is closely associated with prion diseases. PrP will become pathogenic when it undergoes structural change from its native α-helix (cellular PrP, PrPc) to β-sheet conformation (scrapie PrP, PrPsc). The molecular stru...

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Bibliographic Details
Main Authors: Huei-Ying Lian, 連惠瑩
Other Authors: Jerry Chun-Chung Chan
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/18753798147023967508