Novel Mechanism of Cytochrome P450 2E1 Inhibition Protect Against Isoniazid Induced Hepatotoxicity - Quantitative liver function by galactose single point method and application in rat
博士 === 國防醫學院 === 醫學科學研究所 === 99 === Backgrounds and Aims: Cytochrome P450 2E1 (CYP2E1) could play an important role in the pathogenesis of isoniazid (INH)-induced hepatotoxicity. The aim of this study was to prove the concept that apply this mechanism using a CYP2E1 inhibitor, disulfiram (DSF), to p...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2011
|
| Online Access: | http://ndltd.ncl.edu.tw/handle/74561136300501248384 |