Investigation of some selected anthraquinone derivatives as potential PARP inhibitors in lung cancer cells and nuclear reprogramming
碩士 === 國防醫學院 === 藥學研究所 === 99 === The abundant nuclear enzyme poly (ADP-ribose) polymerase-1 (PARP-1), a multifunctional regulator of chromatin structure and DNA repair. High expression of PARP-1 has been indicated in several cancer types, so inhibitors of PARP-1 might be effective as therapeutic ag...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2011
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| Online Access: | http://ndltd.ncl.edu.tw/handle/03400329543827269587 |