Akt Phosphorylation at Thr308 and Ser473 Links Proteasome-mediated Degradation of the Kinase

碩士 === 國立陽明大學 === 生化暨分子生物研究所 === 98 === The master cellular kinase Akt tightly regulates several signal transduction pathways which involve in protein synthesis, cell survival and proliferation, glucose metabolism, etc through its kinase activity. Phosphorylation at Thr308 and Ser473 is known to act...

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Bibliographic Details
Main Authors: Chih-Hao Su, 蘇致豪
Other Authors: Wei-Ping Lee
Format: Others
Language:en_US
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/82422692013911590302