Synthesis and Cytotoxic Activities of 4,5-Disubstituted isoxazoles and pyrazoles

Synthesis and Cytotoxic Activities of 4,5-Disubstituted isoxazoles and pyrazoles

碩士 === 中國文化大學 === 應用化學研究所 === 98 === Abstract Combretastatin A-4 (CA-4), a naturally occurring stilbene, was isolated from Combretum caffrum (African bush willow). CA-4 strongly inhibited the polymerization of tubulin by binding to the colchicine site and showed potent cytotoxicity against a variet...

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Bibliographic Details
Main Authors:	Hon-Cha Huang, 黃浤珈
Other Authors:	Hsi-Lung Yu
Format:	Others
Language:	zh-TW
Published:	2009
Online Access:	http://ndltd.ncl.edu.tw/handle/30026283384892445645

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