Synthesis and Cytotoxic Activities of 4,5-Disubstituted isoxazoles and pyrazoles
碩士 === 中國文化大學 === 應用化學研究所 === 98 === Abstract Combretastatin A-4 (CA-4), a naturally occurring stilbene, was isolated from Combretum caffrum (African bush willow). CA-4 strongly inhibited the polymerization of tubulin by binding to the colchicine site and showed potent cytotoxicity against a variet...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2009
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| Online Access: | http://ndltd.ncl.edu.tw/handle/30026283384892445645 |