Design and Synthesis of 1,4-Dimethylcarbazole and Ellipticine Analogues Containing Benzenesulfonamide Moiety as Potential Anti-cancer Agents
博士 === 臺灣大學 === 藥學研究所 === 98 === Abstract An attempt to develop potent agents to arrest cell cycle, E7010 (6) was chosen as the lead compound. Based on conformational restriction approach, to constrain the secondary amine linkage between pyridine and benzene in E7010 was proposed. Accordingly, 1,4-d...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2010
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| Online Access: | http://ndltd.ncl.edu.tw/handle/52140611308061909449 |