Luminal lipopolysaccharide challenge and commensal bacterial overgrowth induce colonic epithelial cell apoptosis: investigation of the role of CD14 and TLR4 using gene-deficient mouse models

碩士 === 臺灣大學 === 生理學研究所 === 98 === Background: Gram (-) bacterial lipopolysaccharide (LPS) induces innate immune responses via recognition by LPS receptor complex (CD14/TLR4/MD2) on cells of monocytic lineage. LPS binds to cell surface CD14 causing activation of a lipid secondary messenger ceramide a...

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Bibliographic Details
Main Authors: Hsun-Yuan Yang, 楊絢媛
Other Authors: Linda Chia- Hui Yu
Format: Others
Language:zh-TW
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/15508178067902036835