Luminal lipopolysaccharide challenge and commensal bacterial overgrowth induce colonic epithelial cell apoptosis: investigation of the role of CD14 and TLR4 using gene-deficient mouse models
碩士 === 臺灣大學 === 生理學研究所 === 98 === Background: Gram (-) bacterial lipopolysaccharide (LPS) induces innate immune responses via recognition by LPS receptor complex (CD14/TLR4/MD2) on cells of monocytic lineage. LPS binds to cell surface CD14 causing activation of a lipid secondary messenger ceramide a...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Others |
Language: | zh-TW |
Published: |
2010
|
Online Access: | http://ndltd.ncl.edu.tw/handle/15508178067902036835 |