Switching the function of PLP-dependent human serine racemase to serine dehydratase and vice versa by point mutation
碩士 === 臺灣大學 === 生化科學研究所 === 98 === Serine racemase catalyzes the production of D-serine, a co-agonist of the NMDARs in the brain. Mammalian serine racemase is involved in the reversible conversion of L- to D-serine, as well as the dehydration activity toward L- and Dserine. We observed human serine...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2010
|
Online Access: | http://ndltd.ncl.edu.tw/handle/67116262348429902645 |