Switching the function of PLP-dependent human serine racemase to serine dehydratase and vice versa by point mutation

碩士 === 臺灣大學 === 生化科學研究所 === 98 === Serine racemase catalyzes the production of D-serine, a co-agonist of the NMDARs in the brain. Mammalian serine racemase is involved in the reversible conversion of L- to D-serine, as well as the dehydration activity toward L- and Dserine. We observed human serine...

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Bibliographic Details
Main Authors: Cyong-Yi Wang, 王瓊儀
Other Authors: Andrew H.-J. Wang
Format: Others
Language:en_US
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/67116262348429902645