Establishment of an Inducible Cell Model System for Spinocerebellar Ataxia Type 3 Potential Drug Screening

碩士 === 國立臺灣師範大學 === 生命科學研究所 === 98 === Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is the most common autosomal dominant inherited ataxia. SCA3 is caused by a CAG trinucleotide expansion in the MJD1 gene, which is located on chromosome 14q24.3-q31, and translate...

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Bibliographic Details
Main Authors: Hsiao-Hsiu Yen, 顏孝修
Other Authors: Hsiu-Mei Hsieh
Format: Others
Language:en_US
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/06681769489654323319