Nrf2 transcriptional activation by p53 dysfunction promotes tumor progression and associated with poor relapse free survival in lung cancer

碩士 === 中山醫學大學 === 醫學分子毒理學研究所 === 98 === Antioxidant and Phase II detoxification genes regulated by Nrf2-Keap1 signaling pathway may play an important role in lung tumorigenesis. Mutations of Keap1 and Nrf2 genes have been found in lung tumors and both gene mutations increased Nrf2 nuclear translocat...

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Bibliographic Details
Main Authors: Po-Lin, 林伯霖
Other Authors: 李輝
Format: Others
Language:zh-TW
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/60962745338242321124