Study on the phosphorylation sites of DARPP-32 by Cdk5 and preparation of 15N-PKA for NMR study.
碩士 === 國立中正大學 === 生命科學系暨分子生物研究所暨生物醫學研究所 === 98 === DARPP-32 (dopamine and cAMP-regulated phosphoprotein, 32 kD ) is an excellent substrate of PKA and Cdk5. When Thr-34 is phosphorylated by PKA, DARPP-32 will be converted into an inhibitor of PP1 (protein phosphatase 1); while Thr-75 is phosphorylate...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2010
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| Online Access: | http://ndltd.ncl.edu.tw/handle/64895406107265115422 |