The study of inter-molecular interaction between polyQ strands that promote polyQ-containing proteins co-aggregation and the role of Bem2p plays in the DNA stability of repetitive sequence that encodes polyQ

碩士 === 國立陽明大學 === 生化暨分子生物研究所 === 97 === 1.Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder and is caused by the expansion of CAG repeats, encoding polyglutamines (polyQ), within exon 1 of the huntingtin (htt) gene. The length of polyQ track is a main determinant for the...

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Bibliographic Details
Main Authors: Tzu-Han Wang, 王慈涵
Other Authors: Tzu-Hao Cheng
Format: Others
Language:zh-TW
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/21984963689018542246