Inhibition of sialylation of beta1 integrin and CXCR4 by a lithocholic acid-based sialyltransferase inhibitor suppresses cancer metastasis

碩士 === 國立中山大學 === 生物醫學研究所 === 97 === Sialyltransferases (STs), which catalyze the sialylation reaction by adding sialic acids to the terminal positions of oligosaccharide of glycoproteins and glycolipids, are over-expressed in cancer cells and associated with cancer metastasis. Until now, ST inhibit...

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Bibliographic Details
Main Authors: Chi-hsiang Chiang, 江吉祥
Other Authors: Wen-Chun Hung
Format: Others
Language:zh-TW
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/x867qa