Intestinal health promoting effects of multi-ingredient health food formula

• Main Authors: Tsung-Han Chan, 詹宗翰
• Other Authors: 周志輝
• Format: Others
• Language: zh-TW
• Online Access: http://ndltd.ncl.edu.tw/handle/06682338214273013797

碩士 === 國立中興大學 === 食品暨應用生物科技學系 === 97 === The objective of this study was to evaluate the effects of a multi-ingredient health food formula developed with different natural herbal ingredients such as Camellia sinensis, Panax ginseng, Cynara scolymus L. and Auricularia polytricha. The multi-ingredient formula was found to be capable of inhibiting the in vitro activity of α-amylase and suppressing the growth of Staphylococcus aureus. After 30 days of feeding, it was found that the intake of multi-ingredient formula at high dose led to a significant (P < 0.05) increase in fecal dry weight, but no apparent changes in fecal water content were observed. In respect of the activity of different intestinal disaccharidases, the feeding of multi-ingredient formula resulted in significant (P < 0.05) reduction in the maltase and sucrase activities. Regarding the cecal contents of the rats, no changes in the cecal pH and cecal ammonia level were noted after the administration of multi-ingredient formula. The results showed that the fecal mucinase activity was decreased by taking medium dose of multi-ingredient formula. Administration of multi-ingredient formula could promote the proliferation of Bifidobacterium spp. and inhibit the growth of Clostridium perfringens. These results indicated that the administration of multi-ingredient formula might help improve intestinal functions and have the potency to promote health on human intestine. The effects of micronization treatment on the physicochemical properties of the formula were also investigated. Ball milling and high pressure micronization could decrease the particale size and increase the content of soluble polyphenol. Moreover, the multi-ingredient formula could be processed into liposomes of 100 nm in volume mean diameter.