The roles and mechanisms of PAR4 and phosphatidylinositol 3-kinase in maintaining platelet aggregation

碩士 === 高雄醫學大學 === 天然藥物研究所 === 97 === Activation of human platelets by thrombin is mediated predominately through two protease-activated receptors (PARs), PAR1 and PAR4. Inhibition of phosphatidylinositol 3-kinase (PI3K) with wortmannin leads to reverse PAR1-mediated human platelet aggregation, but h...

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Bibliographic Details
Main Authors: Shih-Yun Wu, 吳思筠
Other Authors: Chin-Chung Wu
Format: Others
Language:zh-TW
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/00750109571781484672