G-CSF initiates Akt/GSK3β/NFκB signalings in suppressing the enhanced iNOS expression and NO production in LPS-activated BV-2 microglia

碩士 === 慈濟大學 === 藥理暨毒理學研究所 === 96 === Microglia activation enhances expression of the inducible NO synthase (iNOS) to over produce nitric oxide (NO), leading to neuronal damage. Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and anti-inflammatory effects. None is known about whethe...

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Bibliographic Details
Main Authors: Pin-yun Kao, 高品筠
Other Authors: Jon-Son Kuo
Format: Others
Language:en_US
Online Access:http://ndltd.ncl.edu.tw/handle/45809492049912019048