Molecular Dynamics Simulation of Complexes of Colchicine Binding Site Ligands and Tubulin: Binding Energy Calculation
碩士 === 國立臺灣師範大學 === 化學系 === 96 === Ligands which bind at the colchicine site of tubulin, interfering with tubuline polymerization dynamics, have been showed to have anti-cancer effects. We are interested in drug design of a series of ligands binding at the colchicines binding site of tubulin. We use...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2008
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| Online Access: | http://ndltd.ncl.edu.tw/handle/09932671343559526569 |