The mechanism of overactivation of the Wnt signaling in leukemic cells

碩士 === 國立陽明大學 === 醫學生物技術研究所 === 95 === The Wnt/beta-catenin signaling pathway can promote stem cell self-renewal and is dysregulated in colon carcinoma. Wnt activation leads to beta-catenin accumulation, nuclear translocation and interaction with T-cell factor/ lymphoid enhancer factor (TCF/LEF) tra...

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Bibliographic Details
Main Authors: Jen-Chin Tong, 湯仁智
Other Authors: Chien-Hui Lieu
Format: Others
Language:en_US
Published: 2006
Online Access:http://ndltd.ncl.edu.tw/handle/32640724773793590317