The mechanism of overactivation of the Wnt signaling in leukemic cells
碩士 === 國立陽明大學 === 醫學生物技術研究所 === 95 === The Wnt/beta-catenin signaling pathway can promote stem cell self-renewal and is dysregulated in colon carcinoma. Wnt activation leads to beta-catenin accumulation, nuclear translocation and interaction with T-cell factor/ lymphoid enhancer factor (TCF/LEF) tra...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2006
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Online Access: | http://ndltd.ncl.edu.tw/handle/32640724773793590317 |