Arsenite-elicited Skp2 proteolysis requires lysosomal proteases and kinase-independent functions of p38MAPK
碩士 === 國立清華大學 === 生物科技研究所 === 95 === Abstract Skp2, an F-box protein of SCF E3 ubiquitin ligase, targets key cell cycle regulators for degradation including p21Cip1 and p27Kip1 to timely control the progression from late G1 until mitotic entry, while its protein level is keep low via APCCdh1 and 26S...
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| Format: | Others |
| Language: | en_US |
| Published: |
2007
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| Online Access: | http://ndltd.ncl.edu.tw/handle/23359047172326869842 |