Study of Pregnane X Receptor (PXR) Mutants on CYP3A4 Transactivation Regulation
博士 === 國立成功大學 === 基礎醫學研究所 === 95 === The pregnane X receptor (PXR) is the main transcriptional regulator of many enzymes that metabolize xenobiotics such as P450s and drug transporters. Polymorphisms in the PXR gene contribute to population variability in CYP3A4 and P-glycoprotein levels. Single nuc...
| Main Authors: | , |
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| Format: | Others |
| Language: | en_US |
| Published: |
2007
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| Online Access: | http://ndltd.ncl.edu.tw/handle/47735860757235520000 |