Polyglutamine-expanded ataxin-3- and ataxin-7 upregulate Bax expression and induce apoptotic neuronal death by activating p53.
碩士 === 長庚大學 === 基礎醫學研究所 === 95 === Spinocerebellar ataxia type 3 (SCA3) and spinocerebellar ataxia type 7 (SCA7) are inherited autosomal dominant neurodegenerative disorders caused by abnormal expansion of CAG repeats coding for polyglutamine tract within protein called ataxin-3 and ataxin-7 respect...
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| Format: | Others |
| Language: | en_US |
| Published: |
2007
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| Online Access: | http://ndltd.ncl.edu.tw/handle/51295100544514834489 |