Effect of Denaturants, Organic Solvents and Salts on the Protein Stability, Drug Efficacy, Release and Delivery of the Enediyne Antitumor Antibiotic Chromoprotein, Neocarzinostatin

博士 === 國立中興大學 === 化學系 === 94 === Neocarzinostatin, the antitumor antibiotic chromoprotein from Streptomyces carzinostaicus, is a non-covalent complex of a highly stable all β-sheet apoprotein of 113 amino acids and a labile 9-membered enediyne chromophore. The apoprotein stabilize and transports it...

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Bibliographic Details
Main Authors: G. Christopher Paul Sudhahar, 克利多弗
Other Authors: Der-Hang Chin
Format: Others
Language:en_US
Published: 2005
Online Access:http://ndltd.ncl.edu.tw/handle/80303002055343903267