Effect of Denaturants, Organic Solvents and Salts on the Protein Stability, Drug Efficacy, Release and Delivery of the Enediyne Antitumor Antibiotic Chromoprotein, Neocarzinostatin
博士 === 國立中興大學 === 化學系 === 94 === Neocarzinostatin, the antitumor antibiotic chromoprotein from Streptomyces carzinostaicus, is a non-covalent complex of a highly stable all β-sheet apoprotein of 113 amino acids and a labile 9-membered enediyne chromophore. The apoprotein stabilize and transports it...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2005
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Online Access: | http://ndltd.ncl.edu.tw/handle/80303002055343903267 |