Selective Inhibition Dominant Negative Mutation of p53 by siRNA
碩士 === 國立陽明大學 === 醫學生物技術研究所 === 93 === Mutation of the p53 tumor suppressor gene is the most common genetic alteration in human cancer and the majority of p53 mutations are missense mutations occurring within the DNA-binding domain. These mutants may have a dominant negative effect, i.e. interfering...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2005
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| Online Access: | http://ndltd.ncl.edu.tw/handle/42831830238756608438 |