Design and Synthesis of Anticancer Alkylating Agents of Pyrrolo[2,1-c][1,4]benzodiazepines Hybrid Agents and Containing Sulfur Group in C-ring Analogues
碩士 === 高雄醫學大學 === 醫藥暨應用化學系碩士班 === 93 === 英文摘要 : The pyrrolo [2,1-C] [1,4] benzodiazepines (PBDs), a family of potent DNA-binding antitumor antibiotic are produced by streptomyces species. The PBDs can interact with DNA in a sequence – selective fashion, and form a covalent bond with a guanine...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2005
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| Online Access: | http://ndltd.ncl.edu.tw/handle/03519340176145134119 |