Mechanistic Investigation on mtDNA 8993 T > G Point Mutation-Induced Mitochondrial Dysfunction – role of reactive oxygen species and calcium

碩士 === 長庚大學 === 基礎醫學研究所 === 93 === Mitochondria, not only act as ATP producers through oxidative phosphorylation but also as regulators of intracellular Ca2+ homeostasis and endogenous producers of reactive oxygen species (ROS). Pathogenic mutation of mitochondrial DNA (mtDNA) is often fatal to cell...

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Bibliographic Details
Main Authors: Yu-huei Wang, 王毓慧
Other Authors: Mei-Jei Jou
Format: Others
Language:en_US
Published: 2005
Online Access:http://ndltd.ncl.edu.tw/handle/20241599523846696564