Mechanistic Investigation on mtDNA 8993 T > G Point Mutation-Induced Mitochondrial Dysfunction – role of reactive oxygen species and calcium
碩士 === 長庚大學 === 基礎醫學研究所 === 93 === Mitochondria, not only act as ATP producers through oxidative phosphorylation but also as regulators of intracellular Ca2+ homeostasis and endogenous producers of reactive oxygen species (ROS). Pathogenic mutation of mitochondrial DNA (mtDNA) is often fatal to cell...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2005
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Online Access: | http://ndltd.ncl.edu.tw/handle/20241599523846696564 |