Screening new expandase gene from actinomycetes and using enzyme directed evolution to increase substrate specificity to penicillin G

博士 === 國立陽明大學 === 生物化學研究所 === 92 === Deacetoxycephalosporin C synthase (expandase) from Streptomyces clavuligerus, encoded by cefE, is an important industrial enzyme for the production of 7-aminodeacetoxycephalosporanic acid from penicillin G. To improve the substrate specificity to penicillin G, ei...

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Bibliographic Details
Main Authors: Jyh-Shing Hsu, 許志行
Other Authors: Ying-Chieh Tsai
Format: Others
Language:zh-TW
Published: 2004
Online Access:http://ndltd.ncl.edu.tw/handle/53790727810881711869