Synthesis of a novel Small Molecular Weight Peptidomimetic non-competitive Inhibitors of Protein Tyrosine Phosphatase 1B

碩士 === 國立中央大學 === 化學研究所 === 92 === ABSTRACT There is evidence that type II diabetes has a connection with insulin resistance. Protein tyrosine phosphatase 1B(PTP 1B) attenuates insulin signal transduction by catalyzing the dephosphorylation of the insulin receptors(IR) and is thus a vital target of...

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Bibliographic Details
Main Authors: Chung-Wel Tsai, 蔡宗衛
Other Authors: Wen-Ren Li
Format: Others
Language:zh-TW
Published: 2003
Online Access:http://ndltd.ncl.edu.tw/handle/67424465239606829495