Design and Synthesis of A Ring C8 Substituent and C Ring C2 Oxygenated Pyrrolo[2,1-c][1,4]benzodiazepine as Anticancer Alkylating Agents

碩士 === 高雄醫學大學 === 醫藥暨應用化學系碩士班 === 92 === 英文摘要 Pyrrolo [ 2,1-c ] [ 1,4 ] benzodiazepines (PBDs) were isolated from streptomyces species and belong to an antitumour antibiotic. They can block DNA transcription . These compounds show their biological activity by binding selectively in the minor groo...

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Bibliographic Details
Main Authors: Hua-Ping Chen, 陳華萍
Other Authors: Jeh-Jeng Wang
Format: Others
Language:zh-TW
Published: 2004
Online Access:http://ndltd.ncl.edu.tw/handle/67780950548373491876