Design and Synthesis of A Ring C8 Substituent and C Ring C2 Oxygenated Pyrrolo[2,1-c][1,4]benzodiazepine as Anticancer Alkylating Agents
碩士 === 高雄醫學大學 === 醫藥暨應用化學系碩士班 === 92 === 英文摘要 Pyrrolo [ 2,1-c ] [ 1,4 ] benzodiazepines (PBDs) were isolated from streptomyces species and belong to an antitumour antibiotic. They can block DNA transcription . These compounds show their biological activity by binding selectively in the minor groo...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | zh-TW |
Published: |
2004
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Online Access: | http://ndltd.ncl.edu.tw/handle/67780950548373491876 |